Microbicide Developer Receives License for Novel HIV Microbicide Candidate from Merch & Co., Inc.,International Partnership for Microbicides Press Release, 11 March 2008.

Merck has agreed to provide a full royalty-free license for L’644, a gp41 fusion inhibitor, to the International Partnership for Microbicides (IPM) for development as a potential vaginal microbicide for women in developing countries. Delivery methods under consideration are gels, films or vaginal rings. It’s the sixth drug to be tested by IPM in public-private partnerships with major pharmaceutical companies. Others include a CCR5 blocker by Bristol-Myers Squibb, Merck’s L’167/CMPD167, Pfizer’s maraviroc, Gilead Sciences‘ tenofovir, and Tibotec Pharmaceuticals‘ dapivirine. Dapivirine is expected to enter Phase III clinical trials in 2009.


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