Drug to cure schistosomiasis
Published by AWills March 18th, 2008 in Drug Development, Neglected Diseases“Scientists Identify New Leads for Treating Parasitic Worm Disease,” Eurekalert, 16 March 2008.
Nature Medicine has published a study showing that oxadiazoles can effectively control schistosomiasis. For the past two decades, praziquatel has been the sole drug used to treat this disease in the 70 tropical nations that require annual or semi-annual drug treatment. The oxadiazole compound inhibits the enzyme, thioredoxin glutathione reductase (TGR), which enables the Schistosoma worms to survive within their host organisms.
Links to the popular press:
Julie Steenhuysen, “New Drug Holds Promise for Parasitic Worm Disease,” Reuters, 16 March 2008.
Deborah MacKenzie, “Drug Victory Could Save Thousands From Deadly Worm,” NewScientist.com, 17 March 2008.
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